Neither of these really seem to bother me at all. Once I learned how to reconstitute the Bravelle it was smooth sailing. The Bravelle can burn a bit, but after a while it was fine. I had my husband do the shots the first time around, but the Ovidrel shot made him a bit queasy because of the way it went in my skin. I learned to just do it myself and that made things easier for me.
Each time I'd trigger with the Ovidrel, I knew I ovulated because I could feel the effects. It is amazing all that modern science can do.
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